Overdose of vincristine: experience with a patient
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چکیده
منابع مشابه
Overdose of vincristine: experience with a patient.
Vincristine, referred to as a vinka alkaloid, has been used as a component of the various chemotherapeutic regimens. The major side effects of the usual dosage of vincristine are bone marrow suppression, gastrointestinal disorder, and neurotoxicity. A 53-year-old cervical cancer patient received 14 mg (4 mg/m2/day for 2 days) of vincristine instead of vinblastine because of the similarity betwe...
متن کاملExperience with vincristine--associated neurotoxicity.
OBJECTIVES To evaluate the frequency and severity of occurrence of vincristine-associated neurotoxicity. DESIGN A retrospective case series study. SETTING Hurlingham Oncology Clinic, Nairobi. SUBJECTS Thirty-eight patients treated for various neoplasms with vincristine containing chemotherapeutic regimens. MAIN OUTCOME MEASURES The frequency and degree of neurotoxicity when vincristine ...
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Chemotherapy-induced peripheral neurotoxicity is a major problem because it represents the dose-limiting side effect of a significant number of antineoplastic drugs, such as vinca alkaloids. Hereditary neuropathies usually predispose to severe vincristine neurotoxicity. Here, we report the case of a 56-year-old man with Machado-Joseph disease, also known as spinocerebellar ataxia type 3, treate...
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ژورنال
عنوان ژورنال: Journal of Korean Medical Science
سال: 1998
ISSN: 1011-8934,1598-6357
DOI: 10.3346/jkms.1998.13.3.334